1. SDL: Simple Direct Media Layer.
  2. SDN: Service Delivery Network.
  3. SDR: Software-Defined Radio.
  4. SAN: Storage Area Network.
  5. SATA: Serial ATA.
  6. SAX: Simple API of XML.
  7. SBP-2: Serial Bus Protocol 2.
  8. SBU: Standard Build Unit.
  9. SCSI: Small Computer System Interface.
  10. SDRAM: Synchronous Dynamic Random Access Memory.
  11. SFTP: Secure FTP/Simple File Transfer Protocol.
  12. SHDSL: Single-pair High-speed Digital Subscriber Line.
  13. SPI: Serial Peripheral Interface.
  14. SQL: Structured Query Language.
  15. SUS: Single UNIX Specification.
  16. SVD: Structured VLSI Design.
  17. SVG: Scalable Vector Graphics.
  18. SIMD: Single Instruction, Multiple Data.
  19. SIMM: Single InLine Memory Module.
  20. SMBIOS: System Management BIOS.
  21. SMTP: Simple Mail Transfer Protocol.
  22. SP: Service Pack.
  23. SVGA: Super Video Graphics Array.